它已经表明,胰高糖素像peptide-1(GLP-1)及其稳定和持久的多肽类似物已被确认为施加的影响,如保护神经和抗凋亡缺陷和β-淀粉样蛋白的减少(AB)瘟疫积累(格雷格等,2014)。同时,它调节增强作用和长条款和突触可塑性还有助于促进之间的分化的神经祖细胞。如果观察类似行为在动物中,治疗用GLP-1受体已被证明是一个有益的措施,因为它有助于提高身体的许多认知功能,如提高学习能力和记忆的东西,也有很好的新陈代谢也会导致损失的重量和减少低血糖的风险(鞋底铁掌等,2013)。GLP1治疗的效果的综合评价的情绪障碍患者代表一个数量的可能性。有大量的证据支持的神经保护作用glp – 1在的受体和刺激相同的细胞。因此,需要审查的GLP – 1治疗情绪障碍正在增加。本研究主要是对的好处由GLP-1情绪障碍的治疗。
It has been demonstrated that glucagon like peptide-1 (GLP-1) and its stable and lasting analogues have been identified as the peptides which exerts the effects such as neuro-protective and anti-apoptotic defects and the reduction of the beta-amyloid (AB) plague accumulation (Greig et al, 2014). Also, it modulates the potentiation and synaptic plasticity for a long terms and also helps in the promotion of the differentiation between the of the neuronal progenitor cells. If observing the similar behavior among the animals, the treatment by using the GLP-1 receptors has been demonstrated as a beneficial measure as it helps in the improvement of a number of cognitive functions in the body such as the increase in the ability to learn and memorize the things and also have a good metabolism which also leads to the loss of weight and the reduction of the risk for hypoglycemia (Calkin et al, 2013). The overall evaluation of the effects of GLP1 Treatments in case of the mood disorder patients represents a number of possibilities. There have been a number of evidences which support the neuroprotective role of the GLP-1 receptor and the stimulation of the same in the cells. Thus, the need for the review on the GLP -1 for the treatment of mood disorders is increasing. This research is focused towards the benefits of the treatment of mood disorders by GLP-1.