代写论文的网站:纳米技术对医学的作用

代写论文的网站:纳米技术对医学的作用

目前的技术还没有对脑肿瘤产生积极的预后。脑瘤是恶性的,对全身过程具有侵袭性。初步实验证明纳米医学具有巨大的潜力。纳米技术可以被定义为一种方法,在这种方法中,物质本质上是为许多生物医学用途而创造的。特别是对药物的输送方式给予了很大的重视。最初的实验已经显示了纳米医学的广泛意义。脑肿瘤主要影响血管内皮细胞的选择性,引起血脑肿瘤屏障。纳米管的出现和膜外囊泡的发育已被证明是药物传递[1]的新途径。相对而言,纳米粒子对大脑的渗透性更明显。纳米颗粒显示出治疗脑癌的巨大潜力。它们在促进和提供癌症治疗方面发挥了重要作用。由于这些好处,已经进行了关于大脑细胞通讯和物质和粒子[2]转移的全面研究。尽管有这些进展,但仍有某些因素阻碍了这些治疗癌症的纳米药物的进展。主要问题是纳米药物如何进入大脑。有一些固有的问题,如纳米粒子的消除,证明阻碍了这一进展。除了这个阻碍因素外,还需要考虑纳米颗粒在体内的作用。已经观察到,有一个更高水平的细胞毒性,这是由这种使用。获取纳米药物的最大效率涉及到许多问题。这些因素影响纳米粒子的靶向效率及其分布。了解药物的分子机制和细胞途径对开发新的药物介导传递途径至关重要。量子点、树枝状大分子、金纳米粒子、磁性纳米粒子、纳米管、金纳米线是目前研究用于药物递送的纳米粒子。

本论文主要将重点研究纳米颗粒在细胞转运过程中的传递,并解决药物传递的问题。针对目前治疗性纳米药物的障碍,本研究对不同的纳米颗粒进行了关键分析。在此基础上对研究结果和结论进行了讨论。

代写论文的网站:纳米技术对医学的作用

Current technology does not yield positive prognosis for brain tumor. Brain tumors are malignant and aggressively attack the systemic process. Initial experimentation has proved that there is immense potential for nanomedicine. Nanotechnology can be defined as the method in which substances are essentially created for a number of biomedical usages. Particularly, a lot of emphasis has been given to the modes in which the drugs are delivered. Initial experimentation has shown the vast implications of nanomedicines. Primarily brain tumor affects selective properties of vascular endothelial cells and causes blood-brain-tumor barrier. Advent of nanotubes and development of extra membrane vesicles have proven to be novel pathways for drug delivery [1]. Relatively Nano particles have more visible permeability into the brain. Nanoparticles have shown great potential for treating brain cancer. They have been instrumental in facilitating and providing treatment for cancer. Owing to these benefits there has been comprehensive research undertaken regarding cellular communication in the brain and transfer of materials and particles [2]. In spite of these developments there has been certain factor that impedes the progress of these nanomedicines for treatment of cancer. Main issue is the delivery of nanomedicine into the brain. There are some inherent issues such as elimination of nanoparticles that prove to hinder the progress. Apart from this impeding factor what needs to be counted is the effect of the nanoparticles in vivo. It has been observed that there is a higher level of cellular toxicity that arises from this usage. There are a number of issues involved in procuring maximum efficiency of nanomedicines. These factors affect the targeting efficiency of nanoparticles and its distribution. It is essential to understand the molecular mechanism and cellular pathways to develop novel approaches for drug mediated delivery. Quantum dots, dendrimers, gold nanoparticles, magnetic nanoparticles, nanotubes, gold nanowires are some of the nanoparticles that have been currently investigated for its usage in drug delivery [3].

Primarily this thesis will focus on nanoparticles delivery into the cellular transport process a study and address the issues of drug delivery. For this purpose the current impediments for therapeutic nanomedicines, critical analysis of the different nanoparticles have been undertaken in this research. From this the discussions of the results and conclusions are drawn.